| Acknowledgments | | viii | |
| Foreword | | ix | |
| Preface | | xi | |
| | xix | |
| Color section | | xxv | |
| Section 1 --- Basic concepts: sperm physiology and pathology |
| |
| Anatomy and molecular morphology of the spermatozoon |
| | 3 | |
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| Physiology and pathophysiology of sperm motility |
| | 13 | |
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| The pathophysiology and genetics of human male reproduction |
| | 35 | |
|
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| Contribution of the male gamete to fertilization and embryogenesis |
| | 49 | |
|
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| Genome architecture in human sperm cells: possible implications for male infertility and prediction of pregnancy outcome |
| | 73 | |
|
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| Sperm pathology: pathogenic mechanisms and fertility potential in assisted reproduction |
| | 85 | |
|
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| Testicular dysgenesis syndrome: biological and clinical significance |
| | 105 | |
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| Section 2 --- Diagnosis of male infertility |
| |
| Evaluation of the subfertile male |
| | 117 | |
|
| | 141 | |
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| Advances in automated sperm morphology evaluation |
| | 171 | |
|
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| Sperm morphology training and quality control programs are essential for clinically relevant results |
| | 181 | |
|
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| Role of acrosome index in prediction of fertilization outcome |
| | 187 | |
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| Acrosome reaction: physiology and its value in clinical practice |
| | 195 | |
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| Sperm---zona pellucida binding assays |
| | 209 | |
|
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| Detection of DNA damage in sperm |
| | 225 | |
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| Chromosomal and genetic abnormalities in male infertility |
| | 239 | |
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| Reactive oxygen species and their impact on fertility |
| | 255 | |
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| How do we define male subfertility and what is the prevalence in the general population? |
| | 269 | |
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| DNA fragmentation and its influence on fertilization and pregnancy outcome |
| | 277 | |
|
| The impact of the paternal factor on embryo quality and development: the embryologist's point of view |
| | 291 | |
|
| Section 3 --- Therapeutic alternatives for male infertility |
| |
| Clinical management of male infertility |
| | 305 | |
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| Urological interventions for the treatment of male infertility |
| | 319 | |
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| Medical treatment of male infertility |
| | 333 | |
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| Male tract infections: diagnosis and treatment |
| | 345 | |
|
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| Sperm-washing techniques for the HIV-infected male: rationale and experience |
| | 351 | |
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| Treatment of HIV-discordant couples: the Italian experience |
| | 363 | |
|
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| Artificial insemination using homologous and donor semen |
| | 375 | |
|
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| Intracytoplasmic sperm injection: current status of the technique and outcome |
| | 393 | |
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| Sperm retrieval techniques for intracytoplasmic sperm injection |
| | 401 | |
|
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| Hyaluronic acid binding by sperm: andrology evaluation of male fertility and sperm selection for intracytoplasmic sperm injection |
| | 413 | |
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| In vitro maturation of spermatozoa |
| | 425 | |
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| New developments in the evaluation and management of the infertile male |
| | 453 | |
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| Index | | 461 | |
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