Doctor Dolittle is desperate to write a book about all his animal friends. But his house is so full of animals that he never has a chance to finish all of his jobs and enjoy a moment's peace to write. So, when his friend, Matthew Mugg, suggests a solution to Doctor Dolittle's search for solitude, the Doctor agrees to try it. However, the plan is a little drastic - Matthew's recommendation for peace and quiet is a prison cell. But to find your way in a cell means doing all sorts of naughty things even if your intentions are innocent. Doctor Dolittle will need the help of all his animal friends to get him out of this pickle.