Tuberculosis and Nontuberculous Mycobacterial Infections

TUBERCULOSIS AND NONTUBERCULOUS MYCOBACTERIAL INFECTIONS TUBERCULOSIS AND NONTUBERCULOUS MYCOBACTERIAL INFECTIONS SEVENTH EDITION Complete coverage of every aspect of tuberculosis and related mycobacterial infections “Tuberculosis appears to be as old as humanity itself.” Despite many advancements since the 1882 identification of Mycobacterium tuberculosis as the causative agent of tuberculosis, it remains one of the top 10 causes of death worldwide and threatens the effectiveness of our therapeutic arsenal. In 2015, 1.8 million people died of tuberculosis and almost half a million new cases of multidrug-resistant tuberculosis were diagnosed. For Tuberculosis and Nontuberculous Mycobacterial Infections, Dr. Schlossberg assembled an international team of experts to write about nearly every facet of the prevention, diagnosis, and treatment of tuberculosis and nontuberculous mycobacterial infections. In addition to presenting the latest clinical data, epidemiological findings, and policy and strategy recommendations of the World Health Organization, four new chapters cover topics of critical importance: The role of therapeutic drug monitoring in mycobacterial infections The public health issues of refugees and migrants, and their exposure and transmission of tuberculosis resulting from humanitarian crises Diabetes mellitus as a significant risk factor for tuberculosis The increased risk of tuberculosis reactivation in people taking tumor necrosis factor alpha inhibitors and other biopharmaceuticals Other chapters provide detailed information on the clinical, public health, and policy aspects of tracking and treating tuberculosis, including: The many presentations of tuberculosis, from pulmonary to ocular and cardiovascular to urogenital The complications that tuberculosis and antituberculosis therapy cause to the hematologic and endocrine systems Tuberculosis during pregnancy and in infants and children Treatment of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis Development of new vaccines Nontuberculous infections caused by mycobacteria found throughout our environment The seventh edition of Tuberculosis and Nontuberculous Mycobacterial Infections is an essential resource for anyone working to prevent and treat tuberculosis and associated infections, from infectious disease specialists and pulmonologists to scientists, policymakers, and epidemiologists. A truly modern book that offers students, practitioners, and all readers the chance for a full immersion into the science of tuberculosis.” —MARIO RAVIGLIONE, MD, Global TB Programme, World Health Organization “It’s difficult to improve on an already excellent book but Dr. Schlossberg and colleagues have done it again!” —BURKE A. CUNHA, MD, MACP, Infectious Disease Division, Winthrop-University Hospital “This comprehensive book remains the most popular reference among physicians