ADP-Ribosylation: Metabolic Effects and Regulatory Functions

Joel Moss (Curatore)

Peter Zahradka (Curatore)

Springer-Verlag New York Inc., 2012

Considering the current interest in cellular regulation and intracellular signalling systems, it is surprising that the contribution of ADP-ribosylation reactions to the modulation of a variety of specific cell processes, in parallel with other post-translational modifications such as phosphorylation, has not been generally recognized. While it is not feasible to cover all aspects of ADP-ribosylation, the thirty-one articles contained in this volume provide a valuable overview of recent progress in the field within the context of cell control mechanisms. For the convenience of the reader, the various topics have been grouped into several sections: (a) poly(ADP-ribosyl)ation; (b) mono-ADP-ribosylation; (c) toxin mono-ADP-ribosylation; (d) inhibitors and activators; (e) protein modification with ADP-ribose and its analogues; and (f) non-modification forms of ADP-ribose. The contents of the individual chapters reflect the ideas of the contributors, many of whom have spent their careers attempting to resolve the biological functions of ADP-ribosylation. We hope that this publication will serve as a useful reference for those investigators that are new to the area as well as those who are actively studying ADP-ribosylation.

• Curatore: Joel Moss, Peter Zahradka
• Editore: Springer-Verlag New York Inc.
• Collana: Developments in Molecular and Cellular Biochemistry
• Anno: 2012
• Rilegatura: Paperback / softback
• Pagine: 255 p.
• Dimensioni: 280 x 210 mm
• EAN: 9781461361206

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