Handbook of HER2-targeted agents in breast cancer

di Ricardo H Alvarez (Autore)

Javier Cortés (Autore)

Leticia Mattos-Arruda (Autore)

Springer Healthcare, 2014

?Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women worldwide, accounting for nearly a quarter of the total new cancer cases each year.  Of these cases, approximately  15–25% overexpress HER2, a transmembrane RTK kinase that is associated with aggressive tumor growth and poor outcomes.  However, in the past decade, survival rates of patients with HER-positive breast cancer have significantly improved due to increased screening, HER2 testing, and breakthrough HER2-targeted drug therapies. Handbook of HER2-Targeted Agents in Breast Cancer  provides oncologists, primary care physicians, trainees and other healthcare providers with a concise, accessible, and up-to-date survey of the field, including a review of our current understanding of the biology of the HER2 pathway and the rationale for targeting it in early-stage and advanced breast cancer, an overview of HER2-testing, and evidence-based discussions of available HER2-targeted regimens in the adjuvant and metastatic settings.

• Autore: Ricardo H Alvarez, Javier Cortés, Leticia Mattos-Arruda
• Editore: Springer Healthcare
• Anno: 2014
• Rilegatura: Paperback / softback
• Pagine: 96 p.
• Dimensioni: 201 x 127 mm
• EAN: 9781907673931

Testo in English