Algorithms for Sample Preparation with Microfluidic Lab-on-Chip

di Sukanta Bhattacharjee (Autore)

Bhargab B. Bhattacharya (Autore)

Krishnendu Chakrabarty (Autore)

River Publishers, 2019

Recent microfluidic technologies have brought a complete paradigm shift in automating biochemical processing on a tiny lab-on-chip (a.k.a. biochip) that replaces expensive and bulky instruments traditionally used in implementing bench-top laboratory protocols. Biochips have already made a profound impact on various application domains such as clinical diagnostics, DNA analysis, genetic engineering, and drug discovery, among others. They are capable of precisely manipulating micro-/pico-liter quantities of fluids, and provide integrated support for mixing, storage, transportation, and sensing, on-chip. In almost all bioprotocols, sample preparation plays an important role, which includes dilution and mixing of several fluids satisfying certain volumetric ratios. However, designing algorithms that minimize reactant-cost and sample-preparation time suited for microfluidic chips poses a great challenge from the perspective of protocol mapping, scheduling, and physical design. Algorithms for Sample Preparation with Microfluidic Lab-on-Chip attempts to bridge the widening gap between biologists and engineers by introducing, from the fundamentals, several state-of-the-art computer-aided-design (CAD) algorithms for sample preparation with digital and flow-based microfluidic biochips. Technical topics discussed in the book include: Basics of digital and flow-based microfluidic lab-on-chipComprehensive review of state-of-the-art sample preparation algorithmsSample-preparation algorithms for digital microfluidic lab-on-chipSample-preparation algorithms for flow-based microfluidic lab-on-chip

• Autore: Sukanta Bhattacharjee, Bhargab B. Bhattacharya, Krishnendu Chakrabarty
• Editore: River Publishers
• Anno: 2019
• Rilegatura: Hardback
• Pagine: 178 p.
• Dimensioni: 234 x 156 mm
• Peso: 439 gr.
• EAN: 9788770220552

Testo in English