DECODING BRAIN CANCER: THE BIOLOGY, COMPLEXITY, AND FUTURE OF GLIOBLASTOMA

di Shree Deepti Biyagudem (Autore)

Shree Deepti Biyagudem, 2026

Decoding Brain Cancer The Biology, Complexity, and Future of Glioblastoma Glioblastoma is one of the most difficult cancers to understand and treat. Its aggressiveness is only part of the problem. What makes it so challenging is the complexity of the disease itself. A single tumor can contain different cellular states, interact with neurons, alter its surrounding immune environment, adapt to treatment, and exist within biological barriers that make effective therapy difficult to deliver. Decoding Brain Cancer explores this complexity and how our understanding of glioblastoma has evolved over time. Beginning with the history of neuro-oncology, the book moves from the early study of brain tumors through modern approaches including genomics, single-cell biology, spatial transcriptomics, systems biology, and artificial intelligence. It examines the cellular and immune environment of glioblastoma, mechanisms of treatment resistance and immune evasion, the blood–brain barrier, and the reasons why promising therapies do not always translate into lasting clinical benefit. The book then looks at technologies that are changing how researchers study and approach brain cancer, including extracellular vesicles, nanotechnology, single-cell omics, spatial mapping, bioinformatics, AI, systems biology, and precision oncology. It also considers the limitations of these approaches and where the evidence is still developing. At the centre of the book is a simple question: What changes when we stop thinking of glioblastoma as a single problem and start thinking of it as a dynamic biological system? Written for readers interested in cancer biology, neuroscience, biotechnology, medicine, and the future of healthcare, Decoding Brain Cancer aims to make the biology and research surrounding glioblastoma accessible without reducing its complexity. It does not offer a simple answer to a disease that has resisted one for decades. Instead, it looks at what we know, what we are beginning to understand, and what would need to change for the next generation of discoveries to make a meaningful difference for people diagnosed with glioblastoma.

• Autore: Shree Deepti Biyagudem
• Anno edizione: 2026
• Editore: Shree Deepti Biyagudem
• Formato: EPUB2 con DRMFREE
• Lingua: Inglese
• Compatibilità: Tutti i dispositivi (eccetto Kindle)
• Layout: Reflowable
• EAN: 9798237121124