HIV-1 Latency

Guido Silvestri (Curatore)

Mathias Lichterfeld (Curatore)

Springer Nature Switzerland AG, 2018

This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.

• Curatore: Guido Silvestri, Mathias Lichterfeld
• Editore: Springer Nature Switzerland AG
• Collana: Current Topics in Microbiology and Immunology
• Anno: 2018
• Rilegatura: Hardback
• Pagine: 248 p.
• Dimensioni: 235 x 155 mm
• EAN: 9783030028152

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