Lymphocyte Activation and Immune Regulation IX: Homeostasis and Lymphocyte Traffic

Sudhir Gupta (Curatore)

Eugene Butcher (Curatore)

Springer-Verlag New York Inc., 2012

This volume is divided into three sections. Section I deals with factors that regulate the development and maturation of T cells and B cells and lymphocyte traffic. The significance of C-kit, Bcl-6, IL-7, and Vav in the development of T and B lymphocytes is discussed. A role of lymphotoxins and VAP-I in trafficking of leucocytes is reviewed. Finally, the trafficking and homing characteristics of T cell and B cell subsets, and the regulation of these processes during the immune response, is presented. Section II discusses various aspects of naive and memory T cell biology, including clonal expansion, reprogramming of genes including those encoding cytokines and cytotoxic granules, changes in the expression of cell surface proteins involved in cell-cell adhesion, homing of naive and memory T cells, the role of MHC and cytokines in the maintenance of naive and memory T cells, and the characterization and differentiation of virus-specific memory T cell heterogeneity in mice and humans. Novel methods of visualization of immune cells and immune systems are reviewed in Section III.

• Curatore: Sudhir Gupta, Eugene Butcher
• Editore: Springer-Verlag New York Inc.
• Collana: Advances in Experimental Medicine and Biology
• Anno: 2012
• Rilegatura: Paperback / softback
• Pagine: 212 p.
• Dimensioni: 235 x 155 mm
• EAN: 9781461352266

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