Numerical Methods for the Life Scientist: Binding and Enzyme Kinetics Calculated with GNU Octave and MATLAB

di Heino Prinz (Autore)

Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, 2016

Enzyme kinetics, binding kinetics and pharmacological dose-response curves are currently analyzed by a few standard methods. Some of these, like Michaelis-Menten enzyme kinetics, use plausible approximations, others, like Hill equations for dose-response curves, are outdated. Calculating realistic reaction schemes requires numerical mathematical routines which usually are not covered in the curricula of life science. This textbook will give a step-by-step introduction to numerical solutions of non-linear and differential equations. It will be accompanied with a set of programs to calculate any reaction scheme on any personal computer. Typical examples from analytical biochemistry and pharmacology can be used as versatile templates. When a reaction scheme is applied for data fitting, the resulting parameters may not be unique. Correlation of parameters will be discussed and simplification strategies will be offered.

• Autore: Heino Prinz
• Editore: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
• Anno: 2016
• Rilegatura: Paperback / softback
• Pagine: 149 p.
• Dimensioni: 235 x 155 mm
• EAN: 9783662505878

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