Bacterial Pathogenesis: Methods and Protocols

Frank DeLeo (Curatore)

Michael Otto (Curatore)

Humana Press Inc., 2008

Bacterial infections affect world health today as a leading cause of morbidity and mortality. Pathogenic bacteria routinely command a broad spectrum of niches in the human host, making an understanding of pathogenesis mechanisms crucial to the development of prophylactics and treatment for bacterial diseases. A variety of in vitro methods, in vivo animal model systems and cutting-edge genomics assays have arisen in the effort to study bacterial pathogenesis and identify potential therapeutic targets. In Bacterial Pathogenesis, in-depth methods and state-of-the-art protocols are presented for investigating specific mechanisms of pathogenesis for a wide range of bacteria. This invaluable collection includes protocols to study host-pathogen interactions, animal models of infection, and novel approaches to identifying therapeutic targets designed to control infections. Up-to-date molecular typing methods for Staphylococcus aureus and a new model of streptococcal pharyngitis in non-human primates are also included. Bacterial Pathogenesis will prove an invaluable collection for microbiologists, immunologists, cell biologists and infectious disease clinicians - and indispensable to all science researchers interested in studying pathogenic bacteria and related disease processes.

• Curatore: Frank DeLeo, Michael Otto
• Editore: Humana Press Inc.
• Collana: Methods in Molecular Biology
• Anno: 2008
• Rilegatura: Hardback
• Pagine: 320 p.
• Dimensioni: 235 x 155 mm
• EAN: 9781588297402

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