Biology of Aging, The

di Ray Arters (Autore)

Jayjay Ham LLC, 2025

This audiobook is narrated by a digital voice. Aging represents one of the most fundamental and universal biological processes, yet it remains one of the most complex and poorly understood phenomena in the life sciences. At its core, aging involves the progressive decline in physiological function and increase in mortality risk that occurs with advancing chronological age, manifesting as reduced cellular repair mechanisms, accumulation of molecular damage, and increased susceptibility to disease and death. This process affects virtually all living organisms, from single-celled bacteria to complex multicellular organisms, though the rate and pattern of aging varies dramatically across species and even among individuals within the same species. Understanding the biology of aging requires examining multiple levels of organization, from molecular mechanisms that control cellular senescence to evolutionary forces that shape lifespan and aging patterns across different species. The evolutionary basis of aging presents a fascinating paradox that has puzzled biologists for over a century. From a purely adaptive perspective, aging appears counterproductive, as natural selection should favor organisms that can survive and reproduce indefinitely. However, the universal occurrence of aging across diverse life forms suggests that this process is not merely an accident of biology but rather emerges from fundamental constraints and trade-offs inherent in living systems. Several evolutionary theories have been proposed to explain why aging evolved and persists despite its apparent disadvantages for individual fitness. The mutation accumulation theory proposes that aging results from the accumulation of deleterious mutations that have effects only late in life, when the force of natural selection is weak due to declining reproductive value and increasing extrinsic mortality.

• Autore: Ray Arters
• Durata in (hh:mm:ss): 00:57:01
• Anno edizione: 2025
• Editore: Jayjay Ham LLC
• EAN: 9798318317774

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