Having an understanding of critical appraisal and evidence-based medicine is a prerequisite to being an effective clinician. However, critical appraisal is often taught by people not involved in day-to-day clinical care, meaning the clinical relevance is not always brought to the fore. This book takes a different approach. It is written by clinicians, for clinicians. It takes the reader step by step through the process so that any journal article can be easily read, evidence evaluated and the results - and their reliability - truly understood. By integrating this with knowledge of local skills and resources and patient preference, the reader will be able to apply the best possible care that his or her patients deserve. This accessible book is suitable for undergraduates and postgraduates of all medical specialties, nursing, paramedics, pharmacists and all allied health professions. It is the ideal reference for anyone needing help writing a clinical topic review, reviewing a paper in a journal club or preparing for a critical appraisal exam. But most importantly, it is essential for those who wish to practice medicine in the best possible way for their patients, using the best evidence, tailored to the individual.