Bioconductor Case Studies

di Florian Hahne (Autore)

Wolfgang Huber (Autore)

Robert Gentleman (Autore)

Springer-Verlag New York Inc., 2008

Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. In this volume, the authors present a collection of cases to apply Bioconductor tools in the analysis of microarray gene expression data. Topics covered include: (1) import and preprocessing of data from various sources; (2) statistical modeling of differential gene expression; (3) biological metadata; (4) application of graphs and graph rendering; (5) machine learning for clustering and classification problems; (6) gene set enrichment analysis. Each chapter of this book describes an analysis of real data using hands-on example driven approaches. Short exercises help in the learning process and invite more advanced considerations of key topics. The book is a dynamic document. All the code shown can be executed on a local computer, and readers are able to reproduce every computation, figure, and table.

• Autore: Florian Hahne, Wolfgang Huber, Robert Gentleman
• Editore: Springer-Verlag New York Inc.
• Collana: Use R!
• Anno: 2008
• Rilegatura: Paperback / softback
• Pagine: 284 p.
• Dimensioni: 235 x 155 mm
• EAN: 9780387772394

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